ALTERNATIVE STEROID NAMES: Cyclofenil, Ondogyne, Sexovid.
Testicle Stimulation: Testicle stimulation 7/10
Anti-Estrogen Use: Anti-Estrogen use 6/10
Cutting/Definition: Definition gains 7/10
Side Effects: Side effects 2/10
Ability to keep Gains: Ability to keep gains 1/10
Usual dosages: 400 – 600 mg per day
Detection time: NA
Beginner Use: Use for beginners 8/10
Female Use: Female use 1/10
Pros: Very good all around PCT.
Cons: Hard to finder, More expensive than Clomid of Nolvadex


Cyclofenil is a non-steroidal ancillary drug used by athletes, very similar in action to Clomid and Nolvadex. All three act strongly as estrogen receptor antagonists, which gives them the ability to stimulate ovulation in Women and increase testosterone production in men. For athletic purposes this drug is of most benefit to males, typically used for the purpose of increasing endogenous testosterone levels at the conclusion of a steroid cycle. This is in an attempt to avoid a strong hormonal “crash” while waiting for testosterone levels to be restored. hCG is also commonly used for this purpose, but this drug works by mimicking the action of luteinizing hormone, a much different approach. The effect of hCG is very quick, leading it most often to be the first ancillary drug used after steroids are removed. But drugs like Cyclofenil, Clomid and Nolvadex are better suited for the following weeks usually continued for some time after hCG has been withdrawn. Women do occasionally find a use for antiestrogens, most often around contest time when the management of endogenous estrogens can help increase fat loss and definition. The side effects that can be brought about by a lowering of estrogen activity in the female body however makes this approach less than ideal.

Cyclofenil (like Clomid and Nolvadex) is technically that of an estrogen agonist/antagonist. In the body it displays antiestrogenic properties, affecting the binding efficacy of estrogen receptors in certain target tissues. This is in fact how cyclofenil stimulates the release of testosterone. The hypothalamus is one target site, and here it acts to block the negative feedback inhibition brought fourth by estrogen. The enhanced release of gonadotropin releasing hormone (GnRH) results, which in turn stimulates the pituitary to heighten the release of luteinizing hormone. LH is the primary signal for the testes to increase the production of testosterone, so its increased release leads to an elevation in the androgen level. The antiestrogenic effect of this drug in breast tissue has also led to it during a steroid cycle to prevent gynecomastia, similar to how Nolvadex might be used. Cyclofenil however, is reported to be somewhat weaker than Nolvadex in comparison, and therefore is not usually the preferred estrogen maintenance drug if both were available.

When used after steroids to increase natural testosterone production it can be effective. A dosage of 400-600 mg per day is the most common, generally used for the 4 to 5 weeks following a steroid cycle. It can take a few weeks before Cyclofenil exhibits a noticeable effect, and therefore hCG is usually combined with it for the first week or two. HCG also helps to rapidly restore the ability of the testes to respond to endogenous gonadotropins. which may be notably diminished due to a period of long inactivity. Cyclofenil is continued alone afterwards, with the total duration of ancillary drug use lasting about five or six weeks. It should also be noted that some athletes have experimented with using Cyclofenil not as a post-cycle ancillary drug, but alone as an anabolic. They are hoping that testosterone levels could be raised significantly enough for it to provide some extra muscle mass. Some have reported this approach does work, but results are not extremely significant. Anyone familiar with anabolics would likely be disappointed when using Cyclofenil for this purpose, which is clearly not an equal to injecting testosterone.

Side effects associated with this drug are usually very minimal, and most often are felt my female recipients. The main side effect seen by females tends to be hot flashes due to hormonal changes. In males, the testosterone boosting properties can result in some androgenic effects like oily skin, acne, increased aggression and libido. These are not usually dramatic, as androgen levels will not reach the level seen with most steroids. With Cyclofenil these effects are more welcome than anything, showing the user the drug is having some effect. Here in the U.S., Cyclofenil is not an overly popular item. It is carried on occasion by dealers, but is much less common here than Clomid or Nolvadex. When located in the U.S. it is usually in the form of Fertodur, made by Schering in Europe and (formerly) Mexico.

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