Hydrodiuril (Hydrochlorothiazide)

ALTERNATIVE STEROID NAMES: Hydrodiuril, Hydrochlorothiazide.
ACTIVE SUBSTANCE: Hydrochlorothiazide
Usual dosages: 50 – 200 mg per day


Hydrodiuril is a trade name for the drug hydrochlorthiazide. This is a diuretic from the thiazide family, used medically for the treatment of edemas and hypertension. This drug acts by reducing the reabsorption of electrolytes, thereby increasing the excretion of sodium, potassium, chloride, and consequently water. In comparison to other diuretics, Hydrodiuril is stronger than the potassium sparing agent Aldactone (spironlactone), but weaker then the loop agent Lasix (furosemide). While potassium excretion is much less pronounced than that seen with Lasix, the use of a potassium supplement (or a potassium rich diet) may still be necessary with this product. The necessity for this is usually dependent on the dose and duration in which the drug is administered. Calcium excretion may also be pronounced with thiazides, but again, are weaker in this regard than Lasix.

The use of diuretics has been increasingly popular in a number of athletic disciplines. For starters, these drugs are very popular among bodybuilders who use them to shed subcutaneous water before a competition. The ability to have a winning physique often relies heavily on the definition that can result from diuretic use. The highly defined, super hard and shredded look so common today is nearly impossible to achieve without the use of these drugs. Diuretics are also utilized by athletes who compete in weight categories, using them to drop water weight and make category adjustments. They can allow competitors such as wrestlers and boxers to compete at a much heavier weight during an event than dictated by the “weigh-in” measurement. This is due to the fact that the weight-in is usually done the day before a competition. This allows the athlete to come in light due to diuretics, yet gives enough time to restore fluids and bodyweight before the meet. The result is often a drop of one or more weight categories, a formidable advantage in these types sports. And professional athletes are not the only offenders, as this practice is common in collage sports (sometimes even high schools!). Until the weight-in procedure is placed immediately before the competition, some form of “dropping weight” will always be entertained by such competitors.

The main concern with diuretic use is that it can be a very risky practice. There should be little doubt that diuretics involve a much greater risk to the athlete than that associated with steroid use. Using these drugs incorrectly can produce a dangerous level of dehydration, sometimes to a life threatening point. And unfortunately the line between a shredded physique (or the proper weight class adjustment) and dangerous dehydration is often fine. Sadly, a number of athletes are lost each year when self-administering these drugs, for nothing more than a competitive edge. One should be very careful when using diuretics, hopefully taking time to objectively evaluate the practice. Even when seemingly used correctly, Hydrodiuril can present a number of unwanted side effects to the user. These include, but are not limited to, dehydration, cramping, diarrhea, dizziness, headache, anxiety, unrest, weakness, numbing of extremities and cardiac irregularities. These side effects are generally less pronounced with this class of diuretic (in comparison to loop agents), but should still be a concern. One should take caution by discontinuing this drug should side effects become uncomfortable.

Athletes generally use Hydrodiuril for a short period of time, obviously only needing it for brief water level adjustments. The usual practice is to administer this drug once per day, after the morning meal. The athlete will monitor the level of water lost throughout the day, and adjust the dosage for the following day accordingly. The usual starting dosage is one or two 50 mg tablets. The user will adjust the effect by adding a 25 or 50 mg tablet each subsequent day, with the total dosage not exceeding 200 mg (four 50 mg tablets). This practice is only followed for three or four days, as the user calculates an optimal dosage. If the application of Hydrodiuril is not producing the desired effect, one may choose to addition another diuretic (mild) before moving to the stronger loop agents. A combination of a potassium sparing diuretic like Aldactone (spironolactone) and Hydrodiuril would prove extremely useful, balancing out the calcium and potassium loss of the thiazide. The dosage of each agent would be reduced considerably, perhaps starting with a 50 mg/50 mg application and working upwards. Be careful not to overuse these drugs, as too much water loss will produce a flat, “deflated” looking muscle. More diuretic certainly does not always equate to more definition. It is the best advice to become familiar with this practice well before competition time. Otherwise the user may be left to make frantic dosage adjustments at the last minute, which can be a dangerous practice.

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