Methandriol (Methylandrostendiol/Methylandrostenediol Dipropionate)
SHORT METHANDRIOL DESCRIPTION:
Methandriol Dipropionate is a injectable, strongly anabolic steroid with some androgenic properties. The usual dosage for Methandriol Dipropionate is 100 mg every 2-3 days.
By raising the level of nitrogen retention, Methandriol Dipropionate stimulates protein synthesis, resulting in greater muscle mass; and it increases strength. In addition, it may have anti-catabolic properties. Methandriol Dipropionate is strong enough to be used by alone. However, it is frequently combined with other steroids to enhance the overall effects. Methandriol dipropionate does not directly convert to estrogen, thus it has a low incidence of estrogen-related side effects, such as gynecomastia, water retention, and fat deposition, which are usually minimal if they occur. As Methandriol dipropionate has an androgenic component, typical androgenic-related side effects are possible: oily skin, acne, increased body hair, and scalp hair loss if prone to male pattern baldness.
LONG METHANDRIOL DESCRIPTION:
The steroid Methandriol is manufactured in two very distinct forms. The substance methyiandrostenediol is most commonly seen as an oral compound (although an injectable once existed in the U.S.) and methyiandrostenediol dipropionate which is prepared as an injectable (both forms are thought to have roughly the same effect). The added propionate esters in the injectable form extend the activity of the drug for several days. Basically methandriols are altered forms of the “pro-hormone” 5-androstenediol. This is clear when we look at the chemical structures, as they simply have a methyl group or methyl plus two propionate esters added to the compound (hence the name methyl-androstenediol). Yes, the injectable methandriol does carry both 17alpha methylation and two propionate esters (one at carbon 17, the other at carbon 3). Methandriol was first produced in the United States during the early 1980’s. Power lifting and bodybuilding circles caught on to it quickly, and Methandriol enjoyed a period of great popularity. This did not last very long however, and Methandriol preparations have been unavailable in the states for many years now. Today this steroid is not common on the black market, and is almost exclusively used in Australian veterinary preparations.
Methandriol is thought of as a strong anabolic with notable androgenic properties. It does sometimes display a level of estrogenic activity, so related side effects such as water and fat retention may be of concern (but this is usually dose related). Most of this is due to the fact that 5-androstenediol displays a low affinity to bind and activate the estrogen receptor. There is actually no direct estrogen conversion with this steroid, although since one of its known active metabolites is methyitestosterone we must assume that some aromatization does take place. The properties of this drug are therefore most appropriately suited for the buildup of strength and muscle mass, where any slight estrogenic effect will be less of a concern. For this purpose a typical dosage would be in the range of 25-50 mg daily for the oral form, and 200-400 mg per week with the injectable. In order to keep blood levels more even with the injectable, it is best administered at least every three to four days.
This compound is clearly strong enough to be used alone for muscle building purposes, although methandriol is most often combined with other anabolics for a stronger effect. A cycle of methandriol and Deca-Durabolin or Equipoise (anabolic) for example can produce an exceptional gain of hard, muscle mass, without an extreme level of water retention. This is the general composition of most Australian vet blends that include methandriol. Since the aforementioned drugs do aromatize to some degree however, sensitive individuals may wish to add an antiestrogen such as Nolvadex and/or Proviron to keep related side effects to a minimum. When looking for a more pronounced gain in mass, a stronger androgen such as Dianabol, Anadrol 50 or testosterone could of course be added. The resulting growth can be quite exceptional, but the user will also have to deal with a much stronger set of estrogenic side effects. Likewise the new muscle mass will be accompanied by considerable smoothness due to water retention. Again, the already mentioned antiestrogens could prove very useful. The strong antiaromatase Arimidex may be more applicable in this circumstance, effectively halting estrogen production. This compound is quite expensive however (see: Arimidex).
For contest preparations this steroid can sometimes prove quite useful. With a sufficiently low body fat percentage, the androgenic nature of methandriol can help bring out a look of hardness and density to the muscles. It also combines well with other non-aromatizing anabolics such as Winstrol, Primobolan and oxandrolone. The result here should be an even more pronounced effect on muscle hardness, while at the same time subcutaneous water is kept to a minimum. One may further addition a strong non-aromatizing androgen like Halotestin or trenbolone, but then increases the risk for notable androgenic side effects.
Side effects associated with Methandriol use are generally considered mild. Although estrogenic side effects are sometimes reported with this drug, they do not seem to be a very common problem. One therefore will probably not be faced with heavy water bloat, gynecomastia, increased blood pressure or body fat gain during a cycle unless a very high dosage is used. The most common trouble is likely to come in the form of general androgenic side effects. Oily skin, Acne, body/facial hair growth and hair loss are likewise all possible with methandriol. Since such effects are probably not stemming from the conversion of 5-androstenediol to methyltestosterone and ultimately methyl-DHT (it appears to have a low tendency for this) Proscar would offer us no benefit. Men with a predisposition for male pattern baldness may likewise want to be very cautious when administering this compound. Women should also probably avoid this steroid, as virilization symptoms can occur quickly with the more strongly androgenic drugs.
Since methandriol is a 17-alpha alkylated compound, we do have some additional worries in regard to liver stress. In order to reduce the damaging effect of this substance, cycles are best kept to a minimum. It may also be a good idea to monitor liver values during treatment, particularly if other oral steroids are being used at the same time. The same level of liver stress is not present with the injectable form of course, the body not having to process the 17-methylation all at once. While we cannot exclude the possibility of liver damage with the injectable however, it is still preferred form of administration if both were available.
As discussed earlier, methandriol is not a common inside the U.S. The only place methandriol can be found in abundance is unfortunately Australia. There, a wide number of veterinary preparations include methandriol. These occasionally do reach the U.S., often selling for a high price. The only notable exception to this is the injectable product Denkadiol, sold by Denkall in Mexico. This is the only methandriol reaching the states now in any volume, and is an acceptable buy. Remember to look for the Denkall security hologram when shopping. We also have a couple of oral preparations, manufactured in Yugoslavia and Poland. Again these are quite acceptable, but rarely found in the United States.